> For clean Markdown of any page, append .md to the page URL.
> For a complete documentation index, see https://docs.nvidia.com/clara/parabricks/llms.txt.
> For AI client integration (Claude Code, Cursor, etc.), connect to the MCP server at https://docs.nvidia.com/clara/parabricks/_mcp/server.

# Running NVIDIA Parabricks on nf-core

This guide shows how to run Parabricks on [nf-core](https://nf-co.re/).

Parabricks is an accelerated compute framework that supports applications across the genomics
industry, primarily supporting analytical workflows for DNA, RNA, and somatic mutation detection applications.
With industry leading compute times, Parabricks rapidly converts a FASTQ file to a VCF using multiple, industry
validated variant callers and also includes the ability to QC and annotate those variants. As Parabricks is
based upon publicly available tools, results are easy to verify and combine with other publicly available data sets.

More information is available on the [Parabricks Product Page](https://www.nvidia.com/en-us/clara/genomics/).

Detailed installation, usage, and tuning information is available in the
[Parabricks user guide](https://docs.nvidia.com/clara/parabricks/4.0.0/index.html).

## Finding the Parabricks modules on nf-core

Several Parabricks pipelines can be found on nf-core as modules. These modules
can be dropped into existing workflows or used on their own. To read more about
nf-core modules, refer to the nf-core [documentation](https://nf-co.re/docs/contributing/modules).

To find the available Parabricks modules, visit the [nf-core modules](https://nf-co.re/modules)
page and search for “Parabricks”. The following modules are available:

![](/clara/parabricks/_files/parabricks-clara.docs.buildwithfern.com/aaa5e9e31b5fe41741cf691f90f85100875c7f0df1c46e6fc16cc1e099c69b75/assets/images/CloudGuides/nf-core/available-modules.png)

## Running the Parabricks modules on nf-core

Clicking on any module will take you to the homepage for that module. This page shows the
nf-core CLI command to install this module as well as information about the expected inputs and outputs.

![](/clara/parabricks/_files/parabricks-clara.docs.buildwithfern.com/eff5ddb69e2354575115df3d2068fda7cb550c64a67c090c3e90d47188aa2010/assets/images/CloudGuides/nf-core/running_on_nf-core.png)

This module can be installed by running:

`nf-core modules install parabricks/deepvariant`

And it can be tested locally using:

`nf-core modules test parabricks/deepvariant`

For more details on how to integrate this module into an existing pipeline, refer to the
[nf-core documentation](https://nf-co.re/docs/contributing/tutorials/adding_modules_to_pipelines).