Release Notes

Release 1.0.0

Summary

This is the first release of the Boltz-2 NIM. Boltz-2 enables accurate biomolecular structure prediction from input sequences including proteins, DNA, RNA, and ligands. It also supports constrained guidance for complex structural prediction using bond and pocket specifications.

Notes and Limitations

Ensure you use this NIM with GPUs with at least 48 GB of VRAM.

Note: While there are many options for tuning this NIM’s performance, for most users the defaults will provide a balanced performance experience.