> This page is for Evo 2, version 2.2.0 (Latest) (default).
> For other versions, use one of these documentation indexes:
> - 2.2.0 (Latest) (default): https://docs.nvidia.com/nim/bionemo/evo2/2.2.0/llms.txt
> - 2.1.0: https://docs.nvidia.com/nim/bionemo/evo2/2.1.0/llms.txt
> - 2.0.0: https://docs.nvidia.com/nim/bionemo/evo2/2.0.0/llms.txt
> - 1.0.2: https://docs.nvidia.com/nim/bionemo/evo2/1.0.2/llms.txt
> - 1.0.1: https://docs.nvidia.com/nim/bionemo/evo2/1.0.1/llms.txt
> - 1.0.0: https://docs.nvidia.com/nim/bionemo/evo2/1.0.0/llms.txt

> For clean Markdown of any page, append .md to the page URL.
> For a complete documentation index, see https://docs.nvidia.com/nim/bionemo/llms.txt.
> For AI client integration (Claude Code, Cursor, etc.), connect to the MCP server at https://docs.nvidia.com/nim/bionemo/_mcp/server.

## Release 2.0.0

### Summary

This major release introduces support for loading custom and fine-tuned
checkpoints, enabling users to leverage their own model weights or
community-provided variants. The internal implementation of NIM has migrated to
the [NVIDIA BioNeMo Framework](https://github.com/NVIDIA/bionemo-framework),
providing unified training and inference code bases and standardized
checkpoint formats.

Thanks to the migration to the BioNeMo Framework, new Evo 2 NIM release
delivers up to 30% faster inference workflows compared to the 1.x series.

**Important:** Due to the change in internal model representation, model layer
names and parameter shapes have changed. As a result, `/forward` API calls are
not backward-compatible with 1.x releases.

### Model Variant

* Evo 2 40B 1M