> This page is for MSA Search, version 2.6.0 (Latest) (default).
> For other versions, use one of these documentation indexes:
> - 2.6.0 (Latest) (default): https://docs.nvidia.com/nim/bionemo/msa-search/2.6.0/llms.txt
> - 2.5.0: https://docs.nvidia.com/nim/bionemo/msa-search/2.5.0/llms.txt
> - 2.4.0: https://docs.nvidia.com/nim/bionemo/msa-search/2.4.0/llms.txt
> - 2.3.0: https://docs.nvidia.com/nim/bionemo/msa-search/2.3.0/llms.txt
> - 2.2.0: https://docs.nvidia.com/nim/bionemo/msa-search/2.2.0/llms.txt
> - 2.1.0: https://docs.nvidia.com/nim/bionemo/msa-search/2.1.0/llms.txt
> - 2.0.0: https://docs.nvidia.com/nim/bionemo/msa-search/2.0.0/llms.txt
> - 1.0.0: https://docs.nvidia.com/nim/bionemo/msa-search/1.0.0/llms.txt

> For clean Markdown of any page, append .md to the page URL.
> For a complete documentation index, see https://docs.nvidia.com/nim/bionemo/llms.txt.
> For AI client integration (Claude Code, Cursor, etc.), connect to the MCP server at https://docs.nvidia.com/nim/bionemo/_mcp/server.

## Release 2.5.0

### Summary

This release extends hardware support with NVIDIA B300 data-center GPUs and GB10 (DGX Spark) platforms.

### Hardware Support

The MSA Search NIM now includes support for the following NVIDIA GPUs (in addition to previously supported SKUs):

* **NVIDIA B300**: B300 Tensor Core GPU with 288GB HBM3e memory per GPU (including DGX B300-class deployments)
* **NVIDIA GB10 (DGX Spark)**: Grace Blackwell Superchip with 128GB of unified memory shared between CPU and GPU

Refer to [Prerequisites and Support Matrix](/nim/bionemo/msa-search/prerequisites-and-support-matrix#supported-nvidia-gpus) for memory capacities and recommended GPU counts.

### Migration Notes

No migration steps are required for this release beyond ensuring your driver and container stack meet the [software prerequisites](/nim/bionemo/msa-search/prerequisites-and-support-matrix#software-prerequisites).