Release 1.2.0
Summary
This release introduces support for longer sequence processing and additional GPU compatibility, along with performance optimizations.
Key Features
- Support longer sequence (2048 length) processing for TRT engines on A100, H100, and B200 with memory larger than 48GB
- Support PyTorch and TRT engines with NVIDIA RTX6000 (RTX6000 and RTX6000-Ada GPU Workstation Edition GPU)
- Improve model execution speed
- Optimize memory usage during inference
Release 1.1.0
Summary
Boltz-2 enables accurate biomolecular structure prediction from input sequences including proteins, DNA, RNA, and ligands. It also supports constrained guidance for complex structural prediction using bond and pocket specifications.
This release adds binding affinity prediction for ligands and complexes. The underlying Boltz-2 model has been updated to version 2.2.0. More of the Boltz-2 scores are included in the output. There are minor bug fixes to improve the overall user experience.
Release 1.0.0
Summary
This is the first release of the Boltz-2 NIM. Boltz-2 enables accurate biomolecular structure prediction from input sequences including proteins, DNA, RNA, and ligands. It also supports constrained guidance for complex structural prediction using bond and pocket specifications.