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Release Notes

November 26, 2025

Release 1.1.0

Summary

This release adds support for protein structural template inputs for complex structure prediction, and additional GPU hardware.

New Features

Structural Template Support

The NIM now accepts protein structural template inputs (single-chain) to guide structure prediction:

  • Template input: For each input, protein molecules can include structural templates in CIF format
  • Template guidance: Templates help constrain and improve structure predictions when experimental or predicted structures are available
  • Multiple templates: Each protein can have multiple structural templates

Additional GPU Support

Support for additional NVIDIA GPU configurations:

  • NVIDIA B200: High-performance GPU for large-scale structure prediction
  • NVIDIA L40S: Cost-effective GPU option for production deployments

Telemetry Control

Telemetry control: NIM Telemetry helps NVIDIA deliver a faster, more reliable experience with greater compatibility across a wide range of environments, while maintaining strict privacy protections and giving users full control.

Benefits:

  • Enhances performance and reliability: Provides anonymous system and NIM-level insights that help NVIDIA identify bottlenecks, tune performance across hardware configurations, and improve runtime stability.

  • Improves compatibility across deployments: Helps detect and resolve version, driver, and environment compatibility issues early, reducing friction across diverse infrastructure setups.

  • Accelerates troubleshooting and bug resolution: Allows NVIDIA to diagnose errors and regressions faster, leading to quicker support response times and higher overall availability.

  • Informs smarter optimizations and future releases: Real-world, aggregated telemetry data helps guide the optimization of NIM runtimes, model packaging, and deployment workflows, ensuring updates target the scenarios that matter most to users.

  • Protects user privacy and data security: Collects only minimal, anonymous metadata, such as hardware type and NIM version. No user data, input sequences, or prediction results are collected.

  • Fully optional and configurable: Telemetry collection is disabled by default. You can toggle telemetry at any time using environment variables.

Configuration:

  • Set NIM_TELEMETRY_MODE=0 to disable telemetry (default)
  • Set NIM_TELEMETRY_MODE=1 to enable telemetry

For more information about data privacy, what is collected, and how to configure telemetry, refer to:

Supported Features

All features from release 1.0.0 remain supported, with the addition of structural templates for protein molecules.