Optimizing VM Configuration for Performant AI Inference on Blackwell Ultra HGX# NVIDIA B300 NVL8 full-node passthrough with KVM and libvirt. Introduction About this paper Scope Problem Statement Target Audience Environment System Setup and Installation Blackwell Ultra System Configuration B300 NVL8 Physical Topology Blackwell Ultra System Software Configuration Installing the Hypervisor Understanding system topology Sample ‘lstopo’ output Additional System Setup Considerations Optimal device selection Configuring Virtual Machines VM Configuration Pre-requisites Editing a VM’s XML definition Scenario: Full passthrough- All GPUs, NICs, and NVSwitches Virtual CPU configuration Virtual PCI Express configuration Passthrough device assignment Known Limitations Appendix ATS and ACS configuration Example physical topology map for B300 NVL8 8-GPU platform Example libvirt domain XML for B300 NVL8 8-GPU platform Notices Notice Trademarks Copyright