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Supported Hardware

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The OpenFold2 NIM is configured to run on a single GPU, and supports input sequences with length less than (or-equal-to) 2048 AAs.

GPU

The OpenFold2 NIM is supported to run on the GPU configurations below.

GPUGPU Memory# of GPUs
NVIDIA H100 80GB HBM380GB[1]
NVIDIA H100 PCIe80GB[1]
NVIDIA A100-SXM4-80GB80GB[1]
NVIDIA A100 80GB PCIe80GB[1]
NVIDIA L40S48GB[1]
NVIDIA B200180GB[1]
NVIDIA RTX 6000 Ada Generation48GB[1]
NVIDIA GB200186GB[1]

Storage

NVIDIA recommends at least 80GB of disk space. The container is roughly 55GB. Additionally, at startup, the NIM downloads model parameters (roughly 10GB) if they are not present on the local filesystem.

CPU and System Memory

  • At least 64 GB of RAM
  • A CPU with at least 8 available cores