# Node Locked License, RPM Package Installation

## Prerequisites

Installing Parabricks via the RedHat/RPM bare metal installer requires:

• A working CUDA installation

• An active Anaconda environment

You can test whether you have CUDA installed by running the following:

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nvidia-smi


• CUDA 10.1 for non-Ampere GPUs

• CUDA 11.0 for Ampere GPUs

then you will need to install CUDA. Instructions for doing so can be found at https://developer.nvidia.com/cuda-downloads. Once you have installed CUDA, you may proceed with the following steps.

## Software Installation

To request a trial license, go to https://www.nvidia.com/en-us/clara/genomics/ and click on the "FREE 90-DAY TRIAL" button. You should receive two emails with additional instructions. One tells you how to log on to NGC, the other gives you a direct link to NGC (you'll need to be able to log in to NGC). Following the direct link will let you download "Bare Metal RPM Package" resource, which will result in you downloading a file called files.zip. Once you have downloaded files.zip, go through the following steps:

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# Unzip the downloaded file.  This extracts parabricks.rpm from files.zip
$unzip files.zip # Install the software.$ sudo dnf install -y ./parabricks.rpm

$pbrun version  During the installation you'll be asked 1. To accept the end user license agreement. 2. If you want to create a symbolic link from the Parabricks installation to /usr/bin/pbrun (requires :codesudo access). 3. If you want to install the Ampere version or the non-Ampere version. To check if your system has Ampere GPUs, run the following: Copy Copied!  nvidia-smi --query-gpu=name --format=csv,noheader  Any GPU labeled with the first letter A (e.g. 'Tesla A100', 'Tesla A40') is an Ampere GPU. Note If your machine has more GPUs than you have licenses, you will need to specify which, and how many, GPUs to use. For example, use the following flags to select only the first two GPUs: Copy Copied!  CUDA_VISIBLE_DEVICES="0,1" pbrun [command and inputs] --num-gpus 2  After installation, the pbrun command will start any tool in the Parabricks software suite. Answering "yes" to the second question (about creating a symbolic link) will make pbrun available for system-wide access. Otherwise, you can access pbrun from your local installation directory, which is /opt/parabricks/pbrun by default. ## License Installation To obtain to a permanent node-locked license, run the following command on your GPU server: Copy Copied!  $ nvidia-smi -L

Send the output to parabricks-support@nvidia.com. We will send you a permanent license.bin file, locked to the GPU(s) on that server.
Copy the new license.bin file to /opt/parabricks/license.bin to use your new license.