votebasedvcfmerger
Run votebasedvcfmerger to create union and intersection VCFs based on a minimum number of variant callers supporting a variant.
Earlier versions of Clara Parabricks referred to this as vbvm.
$ pbrun votebasedvcfmerger \
--in-vcf firstfile:/absolute/path/to/input1.vcf \
--in-vcf secondfile:/absolute/path/to/input2.vcf \
--out-vcf output.vcf \
--min-votes 3
Create union and intersection VCFs based on a minimum number of variant callers supporting a variant.
Input/Output file options
- --in-vcf IN_VCF
- --out-dir OUT_DIR
A tag and VCF in the format <tag>:<vcf-file>, where tag can be the name of the variant caller. The VCF file must be an absolute path. This option can be used multiple times, but at least two input VCFs are required. (default: None)
Option is required.
Path for the directory where output VCF files will be created. Two VCFs, unionVCF.vcf and filteredVCF.vcf, will be saved at this location. (default: None)
Option is required.
Tool Option:
- --min-votes MIN_VOTES
- --samples SAMPLES
Minimum number of votes to consider for filtering the VCF. (default: None)
Minimum number of votes to consider for filtering the VCF. (default: None)
Common options:
- --logfile LOGFILE
- --tmp-dir TMP_DIR
- --with-petagene-dir WITH_PETAGENE_DIR
- --keep-tmp
- --license-file LICENSE_FILE
- --no-seccomp-override
- --version
Path to the log file. If not specified, messages will only be written to the standard error output. (default: None)
Full path to the directory where temporary files will be stored.
Full path to the PetaGene installation directory. By default, this should have been installed at /opt/petagene. Use of this option also requires that the PetaLink library has been preloaded by setting the LD_PRELOAD environment variable. Optionally set the PETASUITE_REFPATH and PGCLOUD_CREDPATH environment variables that are used for data and credentials (default: None)
Do not delete the directory storing temporary files after completion.
Path to license file license.bin if not in the installation directory.
Do not override seccomp options for docker (default: None).
View compatible software versions.
GPU options:
- --num-gpus NUM_GPUS
- --gpu-devices GPU_DEVICES
Number of GPUs to use for a run. GPUs 0..(NUM_GPUS-1) will be used.
GPU devices to use for a run. By default, all GPU devices will be used.
To use specific GPU devices, enter a comma-separated list of GPU device
numbers. Possible device numbers can be found by examining the output of
the nvidia-smi command. For example, using --gpu-devices 0,1
would only use the first two GPUs.