Clara Parabricks
v4.0.1
What's New?
Licensing Changes
Supported Tools
WDL/Nextflow Workflows
Improvements
Bug Fixes
Getting Started with Clara Parabricks
Installation Requirements
Hardware Requirements
Software Requirements
Verifying Hardware and Software Requirements
Checking available NVIDIA hardware and driver
Checking available CPU RAM and threads
Checking nvidia-docker2 installation
Checking python version
Getting the Software
Running Clara Parabricks
From the Command Line
Using an AWS AMI
Performance Tuning
Use a Fast SSD
DGX Users
Specifying which GPUs to use
Uninstalling the software
Software Overview
Software Tools
Clara Parabricks WDL/Nextflow Workflows
Compatible CPU Software Versions
Tutorials
Getting The Sample Data
FQ2BAM Tutorial
HaplotypeCaller Tutorial
How-Tos
Whole-Genome Small Variant Calling
Software Requirements
Hardware Requirements
Introduction
Example data
Downloading and Indexing a Reference Genome and Known Sites
Aligning Reads
Generating a Comprehensive Set of Variant Calls with DeepVariant, HaplotypeCaller, and Strelka
Annotating Variant Calls with Information from Databases
Whole-Genome Somatic Small Variant Calling
Software Prerequisites
Compute Requirements and Configuration
Introduction
Download Example FASTQ Files
Downloading and Indexing a Reference Genome and Known Sites
Index Reference Genome
Step1: Aligning the Fastq Files to the Reference Genome
Step2: Generating a Set of Small Variant Calls Using Clara Parabricks Mutect2
Step3: For Validating the SNV and MNV Variants with truth set
Use GATK4 FilterMutectCalls to Apply Filters to the Raw Output of Mutect2
Annotating Variant Calls with Information from Databases
References and Useful Links
Tool Reference
Tools By Category
Tools Alphabetically By Name
Help
Frequently asked questions
User Forum
References
Publications
Academic References to Clara Parabricks
See Also
Third Party Software Notices
ABSEIL
BWA
DEEPVARIANT
GATK
HTSLIB
ISA-L
NUCLEUS
SAMTOOLS
STAR
STAR-FUSION
TCMALLOC
TENSORFLOW
Comparison with Baseline Tools
Comparing BAM Files
Comparing BQSR Reports
Comparing VCF Files
Clara Parabricks
Docs
»
References
References
ΒΆ
Publications
Third Party Software Notices
Comparison with Baseline Tools